Status:
COMPLETED
Translating the DPP Into the Community
Lead Sponsor:
Northwestern University
Collaborating Sponsors:
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Conditions:
Prediabetic State
Overweight
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
The Diabetes Prevention Program (DPP) demonstrated that an intensive lifestyle intervention resulting in modest weight loss and increased physical activity can delay or prevent the development of type...
Eligibility Criteria
Inclusion
- i. 18 years of age or older ii. Body-mass index of \>= 24 kg/m2 iii. ADA diabetes risk assessment score \>= 10 (see below) iv. Casual capillary blood glucose \>= 110 mg/dl
Exclusion
- i. Exclusions for diseases likely to limit life span and/or increase risk of interventions:
- A. Cancer requiring treatment in the past 5 years
- B. Cardiovascular disease:
- A "Yes" response to any item on the modified Physical Activity Readiness Questionnaire (see Appendix 2)
- Uncontrolled hypertension: systolic blood pressure \>180 mmHg or diastolic blood pressure \>105 mmHg
- Heart attack, stroke, or transient ischemic attack in the past 6 months, C. Lung disease: Chronic obstructive airways disease or asthma requiring home oxygen
- ii. Exclusions related to metabolism: A. Diabetes at baseline evaluation B. Casual capillary blood glucose \>= 200 mg/dl C. History of anti-diabetic medication use (oral agents or insulin) except during gestational diabetes
- D. Pregnant female E. Self-report of disease associated with disordered glucose metabolism: Cushing's syndrome; acromegaly; pheochromocytoma; chronic pancreatitis
- iii. Exclusion for conditions or behaviors likely to affect the conduct of the study:
- A. Unable or unwilling to provide informed consent B. Unable to communicate with the pertinent clinic staff C. Unable to read written English
Key Trial Info
Start Date :
May 1 2005
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
August 1 2007
Estimated Enrollment :
92 Patients enrolled
Trial Details
Trial ID
NCT00302042
Start Date
May 1 2005
End Date
August 1 2007
Last Update
July 18 2017
Active Locations (1)
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1
Indiana University Diabetes Prevention and Control Center
Indianapolis, Indiana, United States, 46202