Status:
COMPLETED
Neuroendocrine Mechanisms in Behavioral Treatment of Insomnia
Lead Sponsor:
Brigham and Women's Hospital
Collaborating Sponsors:
National Center for Complementary and Integrative Health (NCCIH)
Conditions:
Insomnia
Eligibility:
All Genders
21-59 years
Phase:
PHASE2
Brief Summary
The purpose of this study is to evaluate the change in measures of physiological arousal before and after behavioral treatment of insomnia.
Detailed Description
There is good evidence that physiological arousal, associated with sustained activation of the hypothalamic-pituitary axis and the sympathetic nervous system, is an underlying cause of chronic insomni...
Eligibility Criteria
Inclusion
- primary insomnia for 6 months
- average total wake time \>60 minutes and sleep efficiency \<80%
- at least 1 daytime complaint due to insomnia
- adequate opportunity and circumstance for sleep
Exclusion
- current psychiatric condition
- medical condition that interferes with sleep
- pregnancy
- rotating shift work, night work or transcontinental travel during study
- anticipated major life stressor over the course of the study
- use of hypnotic or psychoactive medications
- no idiopathic or sleep state misperception insomnia
Key Trial Info
Start Date :
March 1 2006
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
June 1 2009
Estimated Enrollment :
60 Patients enrolled
Trial Details
Trial ID
NCT00303342
Start Date
March 1 2006
End Date
June 1 2009
Last Update
January 14 2010
Active Locations (1)
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1
Sleep Disorders Program, Brigham and Women's Hospital
Boston, Massachusetts, United States, 02115