Status:
TERMINATED
Namenda to Prevent Post-Operative Delirium
Lead Sponsor:
University of Rochester
Collaborating Sponsors:
Forest Laboratories
Conditions:
Delirium
Post-Operative States
Eligibility:
All Genders
50+ years
Phase:
PHASE4
Brief Summary
Post Operative Delirium is a common and serious risk of surgery. Delirium, when it occurs is associated with an increased risk of mortality, increase length of stay, and more adverse outcomes in gener...
Detailed Description
Objectives of this double blind placebo-controlled study are to determine the efficacy, safety and tolerability of Namenda in the prevention of post-operative delirium as defined by DSM-IV-TR categori...
Eligibility Criteria
Inclusion
- Medically stable
- 50 years of age or older
- having elective joint replacement surgery or other orthopedic procedures that are major surgery and require general anesthesia.
Exclusion
- Alcohol or sedative hypnotic abuse or dependence
- Pregnancy
- Dementia or MR/DD patients if they do not have sufficient capacity to understand the consent
- renal impairment or a creatinine of 1.4 or higher
- currently taking cholinesterase inhibitors.
Key Trial Info
Start Date :
March 1 2006
Trial Type :
INTERVENTIONAL
End Date :
September 1 2006
Estimated Enrollment :
30 Patients enrolled
Trial Details
Trial ID
NCT00303433
Start Date
March 1 2006
End Date
September 1 2006
Last Update
June 3 2015
Active Locations (1)
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1
University of Rochester Medical Center
Rochester, New York, United States, 14642