Status:

COMPLETED

Assessment of the Ability to Distinguish Odors in Glaucoma Patients

Lead Sponsor:

University Hospital, Basel, Switzerland

Conditions:

Glaucoma

Eligibility:

All Genders

17-70 years

Brief Summary

Glaucoma is one of the leading causes of blindness worldwide. The key feature of glaucoma is damage to the optic nerve head with loss of retinal ganglion cells and local tissue remodeling. Neuronal ce...

Detailed Description

1. Introduction 1. Background and rationale of the study Glaucoma is one of the leading causes of blindness worldwide. The key feature of glaucoma is damage to the optic nerve head with loss of re...

Eligibility Criteria

Inclusion

  • Chronic open-angle glaucoma with typical glaucomatous disc and visual field damage.

Exclusion

  • Occludable iridocorneal angles
  • History of current, chronic or recurrent inflammatory eye disease
  • History of retinal or neuroophthalmologic disease that could result in visual field defects
  • Need for any concomitant medications that may interfere with the evaluation of olfactory function
  • Patients with a significant history and/or active alcohol or drug abuse (significant is defined as that which in the opinion of the investigator may either put the patient at risk because of participation in the study or may influence the results of the study or the patient's ability to participate in the study), smokers
  • History of olfactory disturbance related to identifiable local factors and any local condition that could lead to hyposmia/anosmia or interfere with the olfactory function, such as polyps, chronic sinus infection, sub(acute) viral or bacterial infection, history of sinus surgery

Key Trial Info

Start Date :

October 1 2004

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

November 1 2005

Estimated Enrollment :

30 Patients enrolled

Trial Details

Trial ID

NCT00304824

Start Date

October 1 2004

End Date

November 1 2005

Last Update

September 26 2008

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