Status:
COMPLETED
Weight Management and Coping Skills Training For Patients With Knee Osteoarthritis
Lead Sponsor:
Duke University
Collaborating Sponsors:
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
Conditions:
Osteoarthritis
Eligibility:
All Genders
18-85 years
Phase:
NA
Brief Summary
Osteoarthritis (OA) occurs when the cartilage between two bones becomes worn down, and the bones begin to rub against each other in the joint. This often leads to pain, swelling, decreased joint motio...
Detailed Description
Osteoarthritis is a chronic, degenerative joint disorder that does not have a cure. While OA can occur at almost any joint, it most commonly occurs in the knee. Obesity is a significant risk factor fo...
Eligibility Criteria
Inclusion
- Meets the American College of Rheumatology criteria for OA
- Radiographic evidence of OA affecting one or both knees
- Complaints of chronic knee pain (pain on most days for at least 6 months prior to study entry)
- No other major weight-bearing joint affected by OA
Exclusion
- Any significant medical condition or disease that would make study participation unsafe or increase the risk of a significant adverse experience during the course of the study (e.g., myocardial infarction in the 6 months prior to study entry)
- Currently involved in a regular exercise program
- An abnormal cardiac response to exercise, such as exercise-induced BT or an abnormal blood pressure response
- A body mass index (BMI) greater than 42
- A non-OA inflammatory arthropathy
- Currently using oral corticosteroids on a regular basis
- Anticipate to have a knee surgery in the next 18 months (or before the anticipated date of their study completion)
- Knee surgery (arthroscopic or knee replacement) within a year of enrollment
- Intraarticular steroid or hyaluronan knee injections in one of both knees within 3 months of enrollment
Key Trial Info
Start Date :
January 1 2004
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
September 1 2009
Estimated Enrollment :
412 Patients enrolled
Trial Details
Trial ID
NCT00305890
Start Date
January 1 2004
End Date
September 1 2009
Last Update
October 25 2018
Active Locations (1)
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1
Duke University Morreene Rd. Clinic
Durham, North Carolina, United States, 27705