Status:
WITHDRAWN
Pioglitazone in Impaired Glucose Tolerance
Lead Sponsor:
University of Leipzig
Collaborating Sponsors:
Institut für Gesundheits- und Praxismanagement GmbH
Conditions:
Glucose Metabolism Disorders
Eligibility:
All Genders
40-75 years
Phase:
PHASE4
Brief Summary
In patients with impaired glucose tolerance (IGT), the researchers want to study the relative effects of pioglitazone, simvastatin, or the combination of both on: * intima media thickness (IMT) as an...
Detailed Description
We want to study the relative effects of pioglitazone, simvastatin or the combination of both on intima media thickness (IMT), heart rate variability (HRV), flow-mediated vasodilatation (FMD) of the b...
Eligibility Criteria
Inclusion
- Impaired glucose tolerance
- Age 40 to 75 years
Exclusion
- Diabetes mellitus type 1 or 2
- Hypersensitivity to study medication
- Malignant tumor
- Alcohol or drug abuse
- Overt heart failure
- Severe hepatic, renal, neurological, psychiatric, or hematological disease
- Prior treatment with glitazones or statins
- Established indication for statin treatment (e.g. coronary artery disease \[CAD\])
Key Trial Info
Start Date :
Trial Type :
INTERVENTIONAL
End Date :
May 1 2009
Estimated Enrollment :
120 Patients enrolled
Trial Details
Trial ID
NCT00306826
End Date
May 1 2009
Last Update
February 2 2010
Active Locations (7)
Enter a location and click search to find clinical trials sorted by distance.
1
Praxis Antje Horn
Gera, Germany, 07548
2
Praxis Gunter Kässner
Leipzig, Germany, 04229
3
Praxis Heidrun Täschner
Leipzig, Germany, 04249
4
Praxis Martin Schönauer
Leipzig, Germany, 04275