Status:

COMPLETED

A Lot-to-lot Consistency (3 Lots of GSK Biologicals' 10-valent Pneumococcal Conjugate Vaccine) & Non-inferiority Study

Lead Sponsor:

GlaxoSmithKline

Conditions:

Infections, Streptococcal

Eligibility:

All Genders

6-12 years

Phase:

PHASE3

Brief Summary

Evaluate lot-to-lot consistency, safety and reactogenicity of 3 doses of GSK Biologicals' 10-valent pneumococcal conjugate vaccine and non-inferiority with respect to Prevenar.

Detailed Description

Test groups: 4 (400 subjects/group). 3 groups receiving 10-valent pneumococcal conjugate vaccine (3 different lots) as follows: - 10-valent vaccine (lot 1, 2 or 3) + DTPa combined vaccine; Control gro...

Eligibility Criteria

Inclusion

  • Inclusion criteria:
  • Male or female between, and including, 6 and 12 weeks (42-90 days) of age at the time of the first vaccination, free of obvious health problems and with written informed consent obtained from the parent/guardian of the subject.
  • Exclusion criteria:
  • Use of any investigational or non-registered drug or vaccine other than the study vaccine within 30 days preceeding the first dose of study vaccine, or planned use during the study period.
  • Planned administration/ administration of a licensed vaccine not foreseen by the study protocol during the period starting from one month before the first dose of vaccine(s) and during the entire study period.

Exclusion

    Key Trial Info

    Start Date :

    November 1 2005

    Trial Type :

    INTERVENTIONAL

    End Date :

    June 1 2006

    Estimated Enrollment :

    1600 Patients enrolled

    Trial Details

    Trial ID

    NCT00307554

    Start Date

    November 1 2005

    End Date

    June 1 2006

    Last Update

    September 26 2016

    Active Locations (35)

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    Page 1 of 9 (35 locations)

    1

    GSK Investigational Site

    Espoo, Finland, 02100

    2

    GSK Investigational Site

    Helsinki, Finland, 00930

    3

    GSK Investigational Site

    Jarvenpaa, Finland, 04400

    4

    GSK Investigational Site

    Jyväskylä, Finland, 40100