Status:

TERMINATED

Comparison Study of Rituximab Plus Sargramostim to Rituximab Alone for Relapsed Follicular B-cell Lymphoma, a Form of Non-Hodgkin's Lymphoma

Lead Sponsor:

Genzyme, a Sanofi Company

Conditions:

Lymphoma, Follicular

Eligibility:

All Genders

18+ years

Phase:

PHASE2

Brief Summary

The purpose of this study is to evaluate whether treatment with rituximab plus sargramostim will be more effective than rituximab alone.

Detailed Description

On 29 May 2009, Bayer began transitioning the sponsorship of this trial to Genzyme. As of 29 August 2009, Genzyme assumed responsibility for the close out of the study. NOTE: This study was originally...

Eligibility Criteria

Inclusion

  • Inclusion Criteria (abbreviated list):
  • Relapsed follicular B-cell lymphoma
  • One or more previous therapies for non-Hodgkin's
  • At least one measurable tumor by CT scan or MRI
  • Additional criteria to be determined at screening visit
  • Exclusion Criteria (abbreviated list):
  • Rituximab refractory (less than 6 months from last treatment with rituximab to relapse)
  • Currently receiving treatment for another cancer
  • Infection currently being treated
  • Active Hepatitis B
  • History of HIV infection
  • Pregnant
  • Additional criteria to be determined at screening visit

Exclusion

    Key Trial Info

    Start Date :

    May 1 2006

    Trial Type :

    INTERVENTIONAL

    Allocation :

    ACTUAL

    End Date :

    June 1 2009

    Estimated Enrollment :

    75 Patients enrolled

    Trial Details

    Trial ID

    NCT00308087

    Start Date

    May 1 2006

    End Date

    June 1 2009

    Last Update

    December 27 2013

    Active Locations (22)

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    Page 1 of 6 (22 locations)

    1

    Birmingham, Alabama, United States, 35234

    2

    Huntsville, Alabama, United States, 35805

    3

    Los Angeles, California, United States, 90095

    4

    Montebello, California, United States, 90640