Status:

COMPLETED

Low-Dose Radiation Therapy in Treating Patients With Follicular or Marginal Zone Non-Hodgkin's Lymphoma

Lead Sponsor:

University College, London

Conditions:

Lymphoma

Eligibility:

All Genders

18+ years

Phase:

PHASE3

Brief Summary

RATIONALE: Radiation therapy uses high-energy x-rays to kill cancer cells. It is not yet known which regimen of low-dose radiation therapy is more effective in treating follicular non-Hodgkin's lympho...

Detailed Description

OBJECTIVES: Primary * Compare the local progression-free interval in patients with follicular non-Hodgkin's lymphoma (NHL) treated with 2 different regimens of low-dose radiotherapy. Secondary * C...

Eligibility Criteria

Inclusion

  • DISEASE CHARACTERISTICS:
  • Histologically confirmed follicular or mmarginal zone non-Hodgkin's lymphoma (NHL)
  • Any stage
  • Radiotherapy is indicated for curative treatment of stage IA or IIA disease OR palliation due to tumor bulk or anatomical position
  • PATIENT CHARACTERISTICS:
  • Life expectancy \> 3 months
  • PRIOR CONCURRENT THERAPY:
  • More than 4 weeks since prior chemotherapy

Exclusion

    Key Trial Info

    Start Date :

    October 1 2005

    Trial Type :

    INTERVENTIONAL

    Allocation :

    ACTUAL

    End Date :

    January 1 2017

    Estimated Enrollment :

    614 Patients enrolled

    Trial Details

    Trial ID

    NCT00310167

    Start Date

    October 1 2005

    End Date

    January 1 2017

    Last Update

    November 17 2017

    Active Locations (1)

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    Cancer Research UK and University College London Cancer Trials Centre

    London, England, United Kingdom, W1T 4TJ