Status:
COMPLETED
Thalamic Deep Brain Stimulation for Tourette Syndrome
Lead Sponsor:
University Hospitals Cleveland Medical Center
Collaborating Sponsors:
Medtronic
Conditions:
Tourette Syndrome
Eligibility:
All Genders
18+ years
Phase:
PHASE2
Brief Summary
The purpose of this study is to determine whether deep brain stimulation is effective at reducing tic frequency and severity in adults with Tourette syndrome.
Eligibility Criteria
Inclusion
- age 18 or older
- Diagnosis of Tourette Syndrome by DSM-IV
- Tic frequency at least one per minute at screening
- prior failure of at least two dopamine receptor or presynaptic blockers
- negative impact on quality of life
Exclusion
- significant structural brain lesion (on imaging studies)
- significant dementia
- severe head trauma preceding onset of tics
- use of dopamine receptor blockers prior to recognition of tics
- prior implanted electrical device
- electroconvulsive therapy (ECT) within 24 months
- suicide attempt within 12 months
- significant sociopathic personality
- current or planned pregnancy
Key Trial Info
Start Date :
June 1 2005
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
April 1 2006
Estimated Enrollment :
5 Patients enrolled
Trial Details
Trial ID
NCT00311909
Start Date
June 1 2005
End Date
April 1 2006
Last Update
May 12 2022
Active Locations (1)
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1
University Hospitals of Cleveland
Cleveland, Ohio, United States, 44106