Status:
COMPLETED
Study Comparing Reducing the Dose of Stavudine Versus Switching to Tenofovir in HIV-Infected Patients Receiving Antiretroviral Therapy
Lead Sponsor:
Hospital Clinic of Barcelona
Conditions:
HIV Infections
Lipoatrophy
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
Background: Stavudine-containing regimens are associated with a potential for lipoatrophy and dyslipidemia. We assessed the safety and efficacy of reducing the dose of stavudine compared to switching ...
Eligibility Criteria
Inclusion
- Study eligibility criteria included documented HIV infection, age 18 years or older, moderate to severe clinical lipoatrophy in at least one region upon physical examination (17,18), viral load \<200 copies/mL for at least 6 months prior to inclusion in the study, and a stable triple antiretroviral therapy including d4T 40 mg bid for at least the 6 preceding months, and no prior TDF use.
Exclusion
- Prior TDF use, viral load\>200 copies.
Key Trial Info
Start Date :
January 1 2004
Trial Type :
INTERVENTIONAL
End Date :
February 1 2005
Estimated Enrollment :
60 Patients enrolled
Trial Details
Trial ID
NCT00312832
Start Date
January 1 2004
End Date
February 1 2005
Last Update
October 24 2006
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