Status:

COMPLETED

A Clinical Trial to Compare Efficacy and Tolerability of Fulvestrant 250mg, 250mg Plus 250mg Loading Regimen and 500mg

Lead Sponsor:

AstraZeneca

Conditions:

Advanced Breast Cancer

Metastatic Breast Cancer

Eligibility:

FEMALE

45-130 years

Phase:

PHASE2

Brief Summary

This study will assess the relationship between fulvestrant dose and efficacy in postmenopausal women with oestrogen receptor positive advanced breast cancer.

Eligibility Criteria

Inclusion

  • Breast Cancer has continued to grow after having received treatment with an anti-estrogen hormonal treatment such as tamoxifen or an aromatase inhibitor.
  • Requiring hormonal treatment.
  • Postmenopausal women (woman who has stopped having menstrual periods)

Exclusion

  • Treatment with more than one previous regimen of systemic anticancer therapy other than endocrine therapy for advanced BC.
  • Treatment with more than one previous regimen of endocrine therapy for advanced BC.
  • An existing condition that prevents compliance.

Key Trial Info

Start Date :

May 30 2006

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

March 13 2019

Estimated Enrollment :

144 Patients enrolled

Trial Details

Trial ID

NCT00313170

Start Date

May 30 2006

End Date

March 13 2019

Last Update

January 6 2020

Active Locations (34)

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Page 1 of 9 (34 locations)

1

Research Site

Brussels, Belgium, 1000

2

Research Site

Leuven, Belgium, 3000

3

Research Site

Roeselare, Belgium, 8800

4

Research Site

Wilrijk, Belgium, 2610