Status:

COMPLETED

Effects of Beta-adrenergic in Adults w/Transposition of Great Arteries on Systemic Ventricular Function

Lead Sponsor:

Emory University

Conditions:

Congenital Disorders

Eligibility:

All Genders

18+ years

Brief Summary

The purpose of this chart review study is to examine the effects of beta -adrenergic blocking agents on systemic ventricular dimensions, systemic atrioventricular valve function and exercise tolerance...

Detailed Description

Many children with transposition of the great arteries who underwent atrial inflow correction using the Mustard or Senning operation are now adults. While their short- and midterm prognosis have been ...

Eligibility Criteria

Inclusion

  • Patients followed-up at Emory University Hospital and The Emory Clinic who meet the following inclusion criteria:
  • Age ≥ 18 years
  • Diagnosis: Complete d-TGA or Congenitally Corrected TGA with a systemic morphologic right ventricle
  • Patients \> 18 years of age seen at The Emory Clinic and Emory University Hospital with transposition of the great arteries
  • Systemic ventricular ejection fraction \< 50% with or without a clinical diagnosis of heart failure
  • Echocardiogram performed between January 1, 1997and February 1, 2006

Exclusion

  • Those who do not meet inclusion criteria.

Key Trial Info

Start Date :

January 1 1997

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

March 1 2007

Estimated Enrollment :

110 Patients enrolled

Trial Details

Trial ID

NCT00313352

Start Date

January 1 1997

End Date

March 1 2007

Last Update

November 13 2013

Active Locations (1)

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1

Emory University

Atlanta, Georgia, United States, 30322