Status:

COMPLETED

Genetic Analysis in Diagnosing Thyroid Cancer in Patients With Thyroid Nodules

Lead Sponsor:

University of California, San Francisco

Collaborating Sponsors:

National Cancer Institute (NCI)

Conditions:

Head and Neck Cancer

Eligibility:

All Genders

18+ years

Phase:

NA

Brief Summary

RATIONALE: Finding genetic markers for thyroid cancer in a biopsy specimen may help doctors diagnose thyroid cancer. PURPOSE: This clinical trial is studying how well genetic analysis works in diagno...

Detailed Description

OBJECTIVES: * Evaluate the diagnostic accuracy of biomarkers and mRNA expression analysis using fine-needle aspiration (FNA) biopsy samples from patients with thyroid nodules. * Correlate the level o...

Eligibility Criteria

Inclusion

  • DISEASE CHARACTERISTICS:
  • Diagnosis of a thyroid nodule that requires fine-needle aspiration biopsy or thyroidectomy to exclude a diagnosis of thyroid cancer
  • PATIENT CHARACTERISTICS:
  • Platelet count ≥ 70,000/mm\^3
  • PT (INR) ≤ 14.5
  • PTT ≤ 35.2
  • Not pregnant
  • PRIOR CONCURRENT THERAPY:
  • No aspirin or nonsteroidal anti-inflammatory drugs (NSAIDs) 7 days before sample procurement

Exclusion

    Key Trial Info

    Start Date :

    July 1 2005

    Trial Type :

    INTERVENTIONAL

    Allocation :

    ESTIMATED

    End Date :

    Estimated Enrollment :

    400 Patients enrolled

    Trial Details

    Trial ID

    NCT00316823

    Start Date

    July 1 2005

    Last Update

    February 24 2014

    Active Locations (1)

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    UCSF Helen Diller Family Comprehensive Cancer Center

    San Francisco, California, United States, 94115