Status:
COMPLETED
Safety and Efficacy Study to Determine Anti-Asthmatic Effect of Esomeprazole Magnesium; Nexium Reflux Asthma
Lead Sponsor:
AstraZeneca
Conditions:
Asthma
GERD
Eligibility:
All Genders
18-70 years
Phase:
PHASE2
Brief Summary
The purpose of this study is to determine whether treatment with esomeprazole for 6 months will improve asthma in adult patients with moderate to severe asthma and symptoms of gastroesophageal reflux ...
Eligibility Criteria
Inclusion
- Adults with diagnosis of asthma since at least 6 months.
- Symptoms of asthma during run-in.
- At least 3 months history and present symptoms of 1 or more of the following: burning feeling behind breastbone, pain behind breastbone, acid taste in the mouth.
Exclusion
- Patients with clinically relevant abnormalities.
- Patients with a smoking history of ≥10 pack-year.
- Patients who have had previous surgery on the esophagus or the stomach.
Key Trial Info
Start Date :
April 1 2006
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
July 1 2008
Estimated Enrollment :
961 Patients enrolled
Trial Details
Trial ID
NCT00317044
Start Date
April 1 2006
End Date
July 1 2008
Last Update
June 9 2014
Active Locations (130)
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1
Research Site
Birmingham, Alabama, United States
2
Research Site
Scottsdale, Arizona, United States
3
Research Site
Little Rock, Arkansas, United States
4
Research Site
Fountain Valley, California, United States