Status:

COMPLETED

Study of Nasal Irrigation Versus Nasal Spray for Chronic Nasal and Sinus Symptoms

Lead Sponsor:

University of Michigan

Collaborating Sponsors:

NeilMed Pharmaceuticals

Conditions:

Chronic Rhinosinusitis

Eligibility:

All Genders

18+ years

Phase:

PHASE4

Brief Summary

This study will compare nasal saline irrigation with nasal saline spray for the treatment of chronic nasal and sinus symptoms. Participants will complete a questionnaire regarding their nasal and sinu...

Detailed Description

See publication: Arch OtolaryngolHeadNeckSurg. 2007;133(11):1115-1120

Eligibility Criteria

Inclusion

  • Age \> 18 years
  • Presence of any one of the following symptoms for \> 4 days/week and \> 15 days in the past 1 month:
  • Nasal stuffiness
  • Nasal congestion
  • Nasal dryness or crusting
  • Abnormal nasal discharge
  • Thick nasal discharge

Exclusion

  • Functional endoscopic sinus surgery (FESS) in the last 3 months
  • Epistaxis in the last 3 months that required treatment
  • Acute illness like otitis media, laryngitis, pharyngitis, or rhinitis in the last 2 weeks
  • Acute attack of asthma or bronchitis in the last 2 weeks
  • Inability to speak or read English
  • Current use of any of the study medications regularly for more than a week in the last 1 month
  • Any history of intolerance to saline treatment (if used)

Key Trial Info

Start Date :

December 1 2005

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

August 1 2006

Estimated Enrollment :

127 Patients enrolled

Trial Details

Trial ID

NCT00318006

Start Date

December 1 2005

End Date

August 1 2006

Last Update

January 30 2015

Active Locations (1)

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1

University of Michigan Health System

Ann Arbor, Michigan, United States, 48109