Status:

TERMINATED

Safety and Efficacy Study of MRE0094 to Treat Large, Single or Multiple, Chronic, Neuropathic, Diabetic Foot Ulcers

Lead Sponsor:

Pfizer

Conditions:

Foot Ulcer, Diabetic

Diabetes Complications

Eligibility:

All Genders

18-85 years

Phase:

PHASE2

Brief Summary

This is a clinical research study of an experimental topical drug for the treatment of chronic, neuropathic, diabetic foot ulcers. The purpose of the study is to determine the safety of the experiment...

Eligibility Criteria

Inclusion

  • Participants included in the study must:
  • Have type 1 or type 2 diabetes mellitus.
  • Have problems with the nerves in their feet.
  • Have a large ulcer or multiple ulcers on the bottom surface of their foot that has been present for 3 weeks or more and is of sufficient size to qualify for the study.
  • Be able to apply study drug to their ulcer, or have a caregiver do it.
  • Be able to visit the doctor regularly during the 4½ month study.

Exclusion

  • Participants may not participate in the study if:
  • Their ulcer is caused by bad blood flow to their foot.
  • Their ulcer is infected.
  • They cannot wear an off-loading device during the study to take pressure off the ulcer.
  • They have certain other diseases, or are using certain types of drugs.

Key Trial Info

Start Date :

June 1 2006

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

February 1 2008

Estimated Enrollment :

16 Patients enrolled

Trial Details

Trial ID

NCT00318214

Start Date

June 1 2006

End Date

February 1 2008

Last Update

June 1 2012

Active Locations (19)

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Page 1 of 5 (19 locations)

1

Associated Foot & Ankle Specialists, LLC

Phoenix, Arizona, United States, 85015

2

Southern Arizona VA Health Care System

Tucson, Arizona, United States, 85723

3

Roy O. Kroeker, DPM

Fresno, California, United States, 93710

4

Innovative Medical Technologies

Los Angeles, California, United States, 90063