Status:
TERMINATED
Treatment of Ragweed-Allergic Asthma With an Immunostimulatory Drug
Lead Sponsor:
National Institute of Allergy and Infectious Diseases (NIAID)
Collaborating Sponsors:
Immune Tolerance Network (ITN)
Conditions:
Asthma
Allergy
Eligibility:
All Genders
18-65 years
Phase:
PHASE2
Brief Summary
This study will test the effectiveness of an investigational treatment for patients with ragweed-induced asthma, sometimes called fall seasonal asthma. The treatment being tested is a series of anti-r...
Detailed Description
Ragweed allergy is a common trigger of asthmatic flare-ups in people with asthma. Individuals with ragweed allergy suffer increased asthma symptoms during the fall allergy season, which generally runs...
Eligibility Criteria
Inclusion
- History of asthma
- History of asthma medication use during the 2005 fall ragweed season
- Suspected ragweed allergy
- Positive laboratory tests for ragweed allergy
Exclusion
- Received immunotherapy for ragweed or other allergens within the 5 years prior to study entry
- Received anti-IgE (omalizumab) within the year prior to study entry
- 3 or more courses of oral corticosteroids for asthma within the year prior to study entry
- Inpatient hospitalization for asthma within the 5 years prior to study entry
- History of respiratory failure or intubation for asthma
- Smoking within the 6 months prior to study entry
- Greater than 5 pack/year history of smoking
- Clinically significant acute or chronic illness
- Chronic immunodeficiency
Key Trial Info
Start Date :
April 1 2006
Trial Type :
INTERVENTIONAL
End Date :
November 1 2006
Estimated Enrollment :
140 Patients enrolled
Trial Details
Trial ID
NCT00318747
Start Date
April 1 2006
End Date
November 1 2006
Last Update
February 5 2013
Active Locations (4)
Enter a location and click search to find clinical trials sorted by distance.
1
Johns Hopkins University
Baltimore, Maryland, United States, 21224
2
Bernstein Clinical Research Center, University of Cincinnati
Cincinnati, Ohio, United States, 452323
3
Optimed Research, Ohio State University
Columbus, Ohio, United States, 43235
4
Pennsylvania State University
Hershey, Pennsylvania, United States, 71033