Status:
COMPLETED
Virulence Determinants in S Aureus Bacteremia
Lead Sponsor:
Duke University
Collaborating Sponsors:
National Institute of Allergy and Infectious Diseases (NIAID)
Conditions:
Bacteremia
Eligibility:
All Genders
18+ years
Brief Summary
The purpose of this study is to investigate why some people develop life-threatening infections caused by the bacteria Staphylococcus aureus, while other people do not. It is possible that the infecti...
Detailed Description
The purpose of this study is to more thoroughly investigate the impact of bacterial genetic characteristics on the outcome of patients with S. aureus bacteremia (SAB). The investigators will address s...
Eligibility Criteria
Inclusion
- Adults (\>= 18 years) with culture-confirmed Staphylococcus aureus bacteremia (SAB). Patients with SAB transferred to Duke University Medical Center are eligible if speculation and antibiotic susceptibilities are confirmed by the Duke Clinical Microbiology Laboratory.
- Absolute neutrophil count of \> 1000 cells/cubic millimeter at the time that the initial positive blood culture is obtained.
- Patient or patient's representative provides signed informed consent allowing study participation.
Exclusion
- Prior enrollment of patient in this investigation (to ensure statistical independence of observations).
- Staphylococcus aureus bacteremia (SAB) that is not confirmed by culture and speciation at the Duke Clinical Microbiology Laboratory.
- Outpatient status.
- Isolation of any pathogen other than S. aureus from bloodstream.
- Inability of patient or patient's representative to provide written informed consent.
Key Trial Info
Start Date :
March 1 2004
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
August 1 2013
Estimated Enrollment :
1354 Patients enrolled
Trial Details
Trial ID
NCT00319826
Start Date
March 1 2004
End Date
August 1 2013
Last Update
April 28 2016
Active Locations (1)
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1
Duke University Medical Center
Durham, North Carolina, United States, 27710