Status:
COMPLETED
The AOT (Acridine Orange and Taurolidine) Trial
Lead Sponsor:
Radboud University Medical Center
Conditions:
Parenteral Nutrition
Infection
Eligibility:
All Genders
18+ years
Phase:
PHASE3
Brief Summary
Total parenteral (intravenous) nutrition in the home setting (Home TPN or HPN) is a life saving strategy in patients who suffer from severe intestinal failure. Unfortunately, this treatment modality r...
Detailed Description
Two hypotheses will be tested in the AOT trial: 1. The use of taurolidine as an antibiotic lock (5 mL) to flush the central line after infusing the TPN formulation, when compared to the present use o...
Eligibility Criteria
Inclusion
- informed consent
- patient on home TPN with central line (Hickman or Porth-a-cath)
- suspected central line infection (acridine orange test)
- proven central line infection (randomisation tauroline vs heparin)
Exclusion
- no informed consent
- patient on home TPN with arteriovenous fistula (shunt)
Key Trial Info
Start Date :
June 1 2006
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
March 1 2008
Estimated Enrollment :
60 Patients enrolled
Trial Details
Trial ID
NCT00321165
Start Date
June 1 2006
End Date
March 1 2008
Last Update
February 11 2009
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Department of Gastroenterology and Hepatology clinical ward
Nijmegen, Netherlands, 6500 HB