Status:
COMPLETED
A Retrospective Analysis of the Use of ACE-inhibitors and Angiotensin Receptor Blockers
Lead Sponsor:
Emory University
Conditions:
Atrial Fibrillation
Atrial Flutter
Eligibility:
All Genders
18-65 years
Brief Summary
It is well known that atrial fibrillation (AF) and atrial flutter occur frequently after most types of cardiac surgeries.(1-4) Postoperative AF is associated with significant morbidity, longer hospita...
Detailed Description
2.0 Objectives Based on the discussion above, we hypothesize that patients premedicated on ACE Inhibitors and ARBs will have a decreased incidence of post-operative AF or atrial flutter. This study w...
Eligibility Criteria
Inclusion
- All patients who underwent elective cardiac surgery in the Emory University Hospital, Crawford Long Hospital, or the VA Medical Center between 2000-2005.
Exclusion
- Emergent operations.
- The presence of AF or atrial flutter at the time of surgery.
- Patients without adequate documentation of atrial rhythm following surgery.
- NYHA class IV heart failure at the time of surgery.
- Hyperthyroidism
- Implanted devices for designed for active management of atrial arrhythmias by pacing or defibrillation
- Known illicit drug use
- Known ethanol abuse
- Electrophysiological ablation for atrial tachycardia within 6 months of the operation.
Key Trial Info
Start Date :
December 1 2005
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
October 1 2009
Estimated Enrollment :
546 Patients enrolled
Trial Details
Trial ID
NCT00321945
Start Date
December 1 2005
End Date
October 1 2009
Last Update
September 27 2013
Active Locations (3)
Enter a location and click search to find clinical trials sorted by distance.
1
Emory University Hospital
Atlanta, Georgia, United States, 30322
2
Crawford Long Hospital
Atlanta, Georgia, United States, 30365
3
Veterans Administration Medical Center
Decatur, Georgia, United States, 30033