Status:
COMPLETED
Naltrexone in the Treatment of Concurrent Alcohol Dependence and Pathological Gambling
Lead Sponsor:
Centre for Addiction and Mental Health
Conditions:
Concurrent Alcohol Dependence and Pathological Gambling
Eligibility:
All Genders
18-65 years
Phase:
NA
Brief Summary
This study assessed whether naltrexone, an opioid antagonist, might be effective in reducing excessive gambling behavior in people who also drink heavily. The efficacy of naltrexone was evaluated in a...
Detailed Description
With the growing popularity of gambling, there has been an increase in the number of individuals with problem gambling. As we learn more about the way we can help problem gamblers, there is a great in...
Eligibility Criteria
Inclusion
- DSM-IV diagnosis of alcohol abuse and dependence
- Diagnosis of pathological gambling
- Drinking on at least 50% of the days in the preceding month
- Gambling at least weekly in the month prior to assessment
Exclusion
- Dependence or abuse of any other psychoactive substances (except for nicotine dependence)
- Concurrent diagnoses of any other psychiatric disorder,
- Serious medical illness
- Laboratory evidence of significant hepatocellular injury
- Use of disulfiramuse and/or opioid-containing medications
- Psychosocial crisis
- Pregnancy
- Inability to read or write English.
- Poor motivation to change alcohol or gambling behavior
Key Trial Info
Start Date :
June 1 2001
Trial Type :
INTERVENTIONAL
End Date :
June 1 2004
Estimated Enrollment :
50 Patients enrolled
Trial Details
Trial ID
NCT00326807
Start Date
June 1 2001
End Date
June 1 2004
Last Update
May 17 2006
Active Locations (2)
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1
Centre for Addiction and Mental Health
Toronto, Ontario, Canada, M5S 2S1
2
National Public Health Institute
Helsinki, Finland, FIN-00101