Status:
COMPLETED
Treatment of Acute Lymphoblastic Leukemia (ALL) in Younger Adults
Lead Sponsor:
Assistance Publique - Hôpitaux de Paris
Collaborating Sponsors:
Group for Research in Adult Acute Lymphoblastic Leukemia
Conditions:
Leukemia, Lymphocytic
Eligibility:
All Genders
18-59 years
Phase:
PHASE3
Brief Summary
This study is a multicenter trial of treatment for young ALL patients. All ALL patients will receive the same steroid pre-phase in order to evaluate sensitivity or resistance. Then, patients will be i...
Detailed Description
GRAALL 2005: T ALL or B ALL non Ph Randomization between standard versus intensified cyclophosphamide administration during a 4-drug, 4 week chemotherapy and late intensification. (N=810 patients pl...
Eligibility Criteria
Inclusion
- 18-59 years
- ALL newly diagnosed (blast \< 20%)
- Central Nervous System (CNS) positive or negative
- Signed written informed consent
- For GRAAPH trial only: t(9;22) or BCR- ABL positive
Exclusion
- Lymphoblastic lymphoma
- ALL 3
- Chronic myeloid leukemia
- Severe organ condition
Key Trial Info
Start Date :
May 1 2006
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
April 1 2014
Estimated Enrollment :
1080 Patients enrolled
Trial Details
Trial ID
NCT00327678
Start Date
May 1 2006
End Date
April 1 2014
Last Update
June 27 2016
Active Locations (1)
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1
Group for Research in Adult Acute Lymphoblastic Leukemia - GRAALL -
Lyon, France, 69