Status:

COMPLETED

Open, Pharmacokinetic Study of Caspofungin in Neonates and Infants (0991-058)

Lead Sponsor:

Merck Sharp & Dohme LLC

Conditions:

Candidiasis

Eligibility:

All Genders

Up to 3 years

Phase:

PHASE2

Brief Summary

The purpose of this study is to test the amount of caspofungin found in the blood of neonate and infants \<3 months of age following treatment with caspofungin at 25 mg/m2. Another purpose is to test ...

Eligibility Criteria

Inclusion

  • Neonates and infants \<3 months of age
  • Patient has a body weight greater than or equal to 500 grams
  • Patient has documented or highly suspected Candida infection

Exclusion

  • Patient is greater than 3 months of age
  • Patient has a body weight of less than 500 grams
  • Patient does not meet certain laboratory testing criteria
  • Patient is hemodynamically unstable, exhibits hemodynamic compromise or is not expected to survive at least 5 days
  • Patient has documented HIV infection of any stage
  • Patient has a history of allergy, hypersensitivity, or serious reaction to caspofungin or another member of the echinocandin class

Key Trial Info

Start Date :

May 1 2006

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

October 1 2006

Estimated Enrollment :

16 Patients enrolled

Trial Details

Trial ID

NCT00330395

Start Date

May 1 2006

End Date

October 1 2006

Last Update

February 23 2017

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