Status:
WITHDRAWN
Effect of Ethanol and Genetic Polymorphisms on Bupropion Metabolism
Lead Sponsor:
Tufts University
Collaborating Sponsors:
National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Conditions:
Alcohol Drinking
Depression
Eligibility:
All Genders
21-55 years
Phase:
NA
Brief Summary
The two purposes of this study are 1. to determine what effect the chronic and moderate/heavy drinking of alcoholic beverages has 1. on the blood level of bupropion and chlorzoxazone and their ma...
Eligibility Criteria
Inclusion
- Healthy adults who are 21 - 55 years of age.
- Either 1) Moderate-to-heavy drinkers who drink on average more than 14 but less than 28 drinks per week; OR 2) adults who normally abstain from drinking alcohol.
Exclusion
- Participants who are currently taking prescription medications (including oral contraceptives)
- Pregnancy
- Body mass index (BMI) greater than 30
- History of seizures or eating disorders
Key Trial Info
Start Date :
December 1 2005
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
April 1 2008
Estimated Enrollment :
Patients enrolled
Trial Details
Trial ID
NCT00330434
Start Date
December 1 2005
End Date
April 1 2008
Last Update
November 10 2020
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Tufts University School of Medicine
Boston, Massachusetts, United States, 02111