Status:

COMPLETED

Intravenous Voriconazole in Patients With Renal Compromise

Lead Sponsor:

University of Pittsburgh

Collaborating Sponsors:

Pfizer

Conditions:

Renal Transplant

Eligibility:

All Genders

18+ years

Brief Summary

The purpose of this study is to determine whether patients with compromised renal function (CrCl \< 50mL/min) receiving intravenous voriconazole experienced any adverse effects related to serum chemis...

Detailed Description

The purpose of this study is to determine whether patients with compromised renal function (CrCl \< 50mL/min) receiving intravenous voriconazole experienced any adverse effects related to serum chemis...

Eligibility Criteria

Inclusion

  • \- Patients \> 18 years old receiving voriconazole with a serum creatinine of \> 2mg/dl (a proxy marker for Creatinine clearance \< 50ml/min). Control group in this study will have serum creatinine \< 1.5mg/dl. Solid organ transplant patient. Patient that received at least 2 doses of voriconazole.

Exclusion

  • None

Key Trial Info

Start Date :

May 1 2006

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

December 1 2015

Estimated Enrollment :

150 Patients enrolled

Trial Details

Trial ID

NCT00332410

Start Date

May 1 2006

End Date

December 1 2015

Last Update

June 12 2018

Active Locations (1)

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1

University of Pittsburgh Medical Center

Pittsburgh, Pennsylvania, United States, 15213