Status:
TERMINATED
Light Therapy for Elderly Depression
Lead Sponsor:
GGZ Buitenamstel
Collaborating Sponsors:
Netherlands Institute for Brain Research, Amsterdam, The Netherlands.
Conditions:
Major Depressive Disorder
Eligibility:
All Genders
60+ years
Phase:
PHASE2
PHASE3
Brief Summary
The purpose of this study is to investigate the following two hypotheses: 1. Treatment with bright light improves their sleep, mood, concentration and self-sufficiency of elderly depressed subjects. ...
Detailed Description
Background: Depression frequently occurs in the elderly. In normal aging, and in depression, the functioning of the suprachiasmatic nucleus (SCN) is impaired, as evidenced by an increased prevalence o...
Eligibility Criteria
Inclusion
- Understanding and speaking Dutch language
- 60 years of age or older
- Presence of a Major Depressive Disorder according to DSM-IV (SCID-based)
- When under treatment of an ophthalmologist, his / her approval for participation.
Exclusion
- Progressive eye diseases, glaucoma or cataract for which an operation is scheduled in near future, aphakia, retinopathies like maculopathy, retinitis pigmentosa or ablatio retina.
- Physical problems or disorders which require specific medical treatment like Lupus, untreated diabetes, malignancies, organic brain disorders, chronic infections, thyroid disorders not adequately treated, thyroid associated ophthalmopathies, M. Parkinson.
- Presence of any concurrent substance abuse problem
- Presence of other actual axis-I disorders like bipolar disorder, dementias, delirium, all psychotic disorders, Posttraumatic stress disorder.
- Use of tricyclic antidepressants, MAOIs.
- Use of corticosteroids.
- Use of tetracyclic antibiotics.
- Treatment with antidepressants shorter than 2 months
- Use of oral contraceptives.
- Treatment with light therapy in the past.
Key Trial Info
Start Date :
January 1 2003
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
June 1 2007
Estimated Enrollment :
89 Patients enrolled
Trial Details
Trial ID
NCT00332670
Start Date
January 1 2003
End Date
June 1 2007
Last Update
August 15 2008
Active Locations (1)
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1
GGZ Buitenamstel
Amsterdam, North Holland, Netherlands, 1081HL