Status:
COMPLETED
Determining Optimal Continuation Treatment Duration for Depressed Children and Adolescents
Lead Sponsor:
University of Texas Southwestern Medical Center
Collaborating Sponsors:
National Institute of Mental Health (NIMH)
Conditions:
Depression
Eligibility:
All Genders
7-18 years
Phase:
NA
Brief Summary
This study will determine the optimal length of continuation treatment with fluoxetine for children and adolescents with major depressive disorder, as well as the factors that may contribute to positi...
Detailed Description
Depression is a serious medical illness that affects all ages and populations. However, it has only been within the last 10 years that sufficient attention has been devoted to researching treatments f...
Eligibility Criteria
Inclusion
- Currently being treated on an outpatient basis
- Currently attending school
- Diagnosis of non-psychotic major depressive disorder (MDD)
- Duration of illness is at least 4 weeks
- In good general medical health
- Normal intelligence
Exclusion
- Lifetime history of any psychotic disorder, including psychotic depression
- Diagnosis of bipolar I or II disorder
- History of alcohol or substance abuse or dependence within 6 months of study entry
- Lifetime history of anorexia nervosa or bulimia
- Pregnant or breastfeeding
- Does not agree to use an effective form of contraception (i.e., IUD, birth control pills, or barrier devices)
- Any chronic medical illness requiring regular medication
- Currently taking medication with psychotropic effects (i.e., anticonvulsants, steroids, etc.), other than stable stimulant treatment
- A first degree relative has bipolar I disorder
- Previous adequate treatment with fluoxetine was ineffective (defined as at least 20 mg/day for 4 weeks)
Key Trial Info
Start Date :
June 1 2000
Trial Type :
INTERVENTIONAL
End Date :
October 1 2005
Estimated Enrollment :
200 Patients enrolled
Trial Details
Trial ID
NCT00332787
Start Date
June 1 2000
End Date
October 1 2005
Last Update
January 8 2014
Active Locations (1)
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1
Children's Medical Center at Dallas, Outpatient Psychiatry Clinic
Dallas, Texas, United States, 75235