Status:
WITHDRAWN
Effect of Dexmedetomidine Upon Sleep Postoperatively
Lead Sponsor:
Duke University
Conditions:
Sleep
Eligibility:
All Genders
21-50 years
Phase:
PHASE4
Brief Summary
The purpose of this study is to determine whether an intravenous infusion of dexmedetomidine administered to surgical patients intra-operatively will improve the characteristics of sleep post-operativ...
Detailed Description
Physiological similarities exist between the anesthetized state and sleep. Pathways within the brain controlling sleep and wakefulness are also affected by anesthesia. One significant difference betwe...
Eligibility Criteria
Inclusion
- scheduled to undergo elective lower extremity orthopaedic surgery (free vascular fibular graft)
- ASA 1 or 2
- Body Mass Index 20 - 30
- Procedure to be done under combined epidural and general anesthesia
Exclusion
- Sleep disturbance
- Insomnia
- Sleep apnea
- Female (pregnant)
- Contra-indication to placement of epidural anesthesia
Key Trial Info
Start Date :
June 1 2006
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
June 1 2011
Estimated Enrollment :
Patients enrolled
Trial Details
Trial ID
NCT00333632
Start Date
June 1 2006
End Date
June 1 2011
Last Update
July 14 2014
Active Locations (1)
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1
Duke University Medical Center
Durham, North Carolina, United States, 27710