Status:
COMPLETED
Post Conditioning in PCI for Acute ST Elevation Myocardial Infarction
Lead Sponsor:
University of Calgary
Collaborating Sponsors:
Foothills Interventional Cardiology Research Group
Conditions:
Myocardial Infarction
Eligibility:
All Genders
18-80 years
Phase:
PHASE4
Brief Summary
The purpose of this trial is to compare post-conditioning to standard angioplasty (50/50 chance) in patients who present with an acute heart attack and are taken directly for an angioplasty procedure....
Detailed Description
In patients who suffer a myocardial infarction, the blood flow usually ceases due to plaque rupture leading to thrombus formation and vessel occlusion. The resultant entity is known as ST Elevation se...
Eligibility Criteria
Inclusion
- 18 years and over
- ST elevation of \>/= 2mm in 3 consecutive anterior leads or \>/= to 2 mm in leads II, III and AVF with total 8 mm ST shift (ST depression of 1 mm in ant or lat leads)
Exclusion
- Cardiogenic shock or severe heart failure
- Inability to undergo CMR (metallic objects or claustrophobia)
- Previous MI
- TIMI 2-3 flow in target artery
- Collaterals to infarct related artery \> Rentrop grade 1
- Inability to undertake successful PCI at time of angio
- Significant LM disease or requiring CABG during hospital stay
- Inability to proceed with post conditioning within 1 minute of establishing blood flow in culprit artery
Key Trial Info
Start Date :
June 1 2006
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
October 1 2011
Estimated Enrollment :
102 Patients enrolled
Trial Details
Trial ID
NCT00334373
Start Date
June 1 2006
End Date
October 1 2011
Last Update
May 28 2015
Active Locations (1)
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1
Foothills Medical Centre
Calgary, Alberta, Canada, T2N 2T9