Status:
COMPLETED
Exercise in Improving Mobility and Reducing Fatigue and/or Weakness in Older Cancer Survivors
Lead Sponsor:
University of Utah
Collaborating Sponsors:
National Cancer Institute (NCI)
Conditions:
Bladder Cancer
Breast Cancer
Eligibility:
All Genders
60+ years
Phase:
NA
Brief Summary
RATIONALE: Exercise may help improve mobility and relieve fatigue and/or weakness in cancer survivors. It is not yet known whether exercise is more effective than standard therapy in improving mobilit...
Detailed Description
OBJECTIVES: * Compare the perception of, and the patterns of change in fatigue, weakness, physical activity level, and functional status in elderly cancer survivors who undergo Resistance Exercise vi...
Eligibility Criteria
Inclusion
- DISEASE CHARACTERISTICS:
- Survivor of breast, prostate, colon, lung, lymphoma, ovarian, bladder, or esophageal cancer with no evidence of disease
- At least moderate levels of fatigue and/or weakness
- Impaired mobility but ambulatory and medically able to participate in an exercise regimen
- No impaired knee flexion, defined as \< 90º
- PATIENT CHARACTERISTICS:
- Folstein Mini-Mental Status Examination score ≥ 23
- No extreme claustrophobia
- No diagnosed chronic fatigue syndrome/disorder
- No neurological impairments, including the following:
- Central nervous system disorder (e.g., multiple sclerosis or Parkinson's disease)
- Neurological insult (cerebrovascular attack) that manifests in a mobility disorder
- No myopathic disease (e.g., focal myopathy) that effects skeletal muscle structure/function
- No rheumatological disease that has an effect on muscle and/or mobility (e.g., polymyalgia rheumatica)
- PRIOR CONCURRENT THERAPY:
- More than 6 months since prior regular aerobic or resistance exercise
- Regular exercise defined as 2-3 times per week
- At least 6 months since prior cancer treatment (surgery, radiation, and/or chemotherapy )
- No concurrent cancer-related treatment other than hormonal therapy
Exclusion
Key Trial Info
Start Date :
March 1 2006
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
March 1 2010
Estimated Enrollment :
49 Patients enrolled
Trial Details
Trial ID
NCT00335491
Start Date
March 1 2006
End Date
March 1 2010
Last Update
September 30 2011
Active Locations (1)
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1
Huntsman Cancer Institute at University of Utah
Salt Lake City, Utah, United States, 84112