Status:

ENROLLING_BY_INVITATION

External Influences Upon Ocular Homeostasis

Lead Sponsor:

Vanderbilt University Medical Center

Conditions:

Intraocular Pressure

Eligibility:

All Genders

10-90 years

Phase:

NA

Brief Summary

Our experiments are designed to test the overall hypothesis that position-dependent or water-dependent intra-ocular pressure (IOP) spikes occur in humans, and that these challenge ocular homeostasis.

Detailed Description

Glaucoma is the second leading cause of blindness in the United States, yet its pathogenesis is poorly understood. This is an insidious disorder since the loss of peripheral vision which occurs first ...

Eligibility Criteria

Inclusion

  • Inclusion Criteria:
  • Patients with autonomic dysfunction
  • Patients with open-angle glaucoma
  • Patients with normal-pressure glaucoma
  • Normal subjects
  • Exclusion criteria:
  • Medical students
  • Prisoners
  • Pregnant women

Exclusion

    Key Trial Info

    Start Date :

    June 1 2006

    Trial Type :

    INTERVENTIONAL

    Allocation :

    ESTIMATED

    End Date :

    December 1 2027

    Estimated Enrollment :

    200 Patients enrolled

    Trial Details

    Trial ID

    NCT00338065

    Start Date

    June 1 2006

    End Date

    December 1 2027

    Last Update

    December 29 2025

    Active Locations (1)

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    1

    Vanderbilt University

    Nashville, Tennessee, United States, 37232