Status:
COMPLETED
"Red Morphine Drops" for Symptomatic Treatment of Dyspnoea in Lung Cancer
Lead Sponsor:
Sankt Lukas Hospice
Conditions:
Dyspnea
Lung Neoplasms
Eligibility:
All Genders
18+ years
Phase:
PHASE4
Brief Summary
The purpose of this study is to test whether "red morphine drops" applied in the mouth are superior to an equivalent amount of morphine applied as subcutaneous injection for the relief of breathlessne...
Detailed Description
Breathlessness or dyspnea in terminal cancer patients with lung cancer is common and opioids such as morphine is the mainstay of symptomatic treatment. Subcutaneous administration of morphine provides...
Eligibility Criteria
Inclusion
- Primary lung cancer or lung metastases and
- Moderate to severe dyspnea at rest (VAS equal to or more than 30)
Exclusion
- Causal treatment of dyspnea possible and indicated
- Not receiving opioids on a regular basis
- Methadone treatment
- Intolerance to morphine
- Without understanding of patient information
- Depressed consciousness
- Oxygen treatment, if changed with-in 20 min before start
- Short-acting opioids with-in 4 h before start
- Inhalation therapy for bronchodilation with-in 20 min before start
Key Trial Info
Start Date :
April 1 2006
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
February 1 2011
Estimated Enrollment :
20 Patients enrolled
Trial Details
Trial ID
NCT00338481
Start Date
April 1 2006
End Date
February 1 2011
Last Update
July 27 2011
Active Locations (1)
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1
Sankt Lukas Hospice
Copenhagen, Hellerup, Denmark, 2900