Status:
COMPLETED
Corticosteroids in the Treatment of Tuberculous Pleurisy
Lead Sponsor:
Guangxi Medical University
Collaborating Sponsors:
National Natural Science Foundation of China
Ministry of Education, China
Conditions:
Tuberculous Pleurisy
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
Tuberculous pleurisy is associated with inflammation and fibrosis. Adjunctive corticosteroids are used for tuberculous pleurisy because their anti-inflammatory effect is thought to minimise pleural re...
Eligibility Criteria
Inclusion
- Signed written informed consent;
- Presented with clinical features suggesting pleural tuberculosis;
- Had not previously received treatment or prophylaxis for tuberculosis;
- Had not recently received treatment with glucocorticoids;
- Were not pregnant or breast-feeding.
Exclusion
- Failed to complete the screening procedures;
- Were seropositive for HIV
- Tuberculous meningitis;
- Had risk factors for serious steroid-related adverse events (a history of diabetes or positive urine glucose, a history or clinical finding of hypertension, or a history of peptic ulcer disease or mental illness);
- Standard doses of antituberculosis drugs could not be used (as in participants with concurrent liver disease)
- Psychiatric illness;
- Alcoholism.
Key Trial Info
Start Date :
July 1 2006
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
August 1 2008
Estimated Enrollment :
1500 Patients enrolled
Trial Details
Trial ID
NCT00338793
Start Date
July 1 2006
End Date
August 1 2008
Last Update
August 26 2008
Active Locations (1)
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1
Huan-Zhong Shi
Nanning, Guangxi, China, 530021