Status:
COMPLETED
Levels of Bisphenol A in Urine and Saliva Following Placement of Composite Restorations
Lead Sponsor:
National Institute of Dental and Craniofacial Research (NIDCR)
Conditions:
Dental Restorations
Eligibility:
All Genders
20-60 years
Brief Summary
This study will determine whether placement of composite (white) dental restorations (fillings) increases concentrations of bisphenol A (BPA) and its metabolites in saliva and urine. These compounds h...
Detailed Description
A study by Olea et al in 1996 reported quantities of specific estrogenic compounds, Bisphenol A (BPA), bis-glycidyl methacrylate (bis-GMA) and Bis-A-dimethacrylate (bis-DMA) in saliva associated with ...
Eligibility Criteria
Inclusion
- INCLUSION CRITERIA:
- Individual patients who require at least one restoration are eligible. We will give preference to patients who require multiple restorations that qualify for a composite filling material. Every attempt will be made to adequately represent women and minorities into the study.
- EXCLUSION CRITERIA:
- Individual patients who have received composite restorations or pit and fissure sealants during the past 3 months and individuals who wear removable dental appliances, such as orthodontic retainers or partial dentures, will be excluded.
Exclusion
Key Trial Info
Start Date :
July 26 2004
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
January 22 2013
Estimated Enrollment :
172 Patients enrolled
Trial Details
Trial ID
NCT00339339
Start Date
July 26 2004
End Date
January 22 2013
Last Update
December 17 2019
Active Locations (2)
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1
Commissioned Officers Dental Clinic (CODC)
Rockville, Maryland, United States
2
Kessler Air Force Base Dental Clinic
Biloxi, Mississippi, United States, 39534-2519