Status:

COMPLETED

PK/PD, Long-term Safety and Efficacy of Tamsulosin Treatment in Children With Neurogenic Bladder

Lead Sponsor:

Boehringer Ingelheim

Conditions:

Bladder, Neurogenic

Eligibility:

All Genders

2-16 years

Phase:

PHASE2

Brief Summary

Aims of this study is to characterize the pharmacokinetic/pharmacodynamic profile and evaluate the safety, efficacy and tolerability, of tamsulosin hydrochloride as treatment in children with a neurop...

Eligibility Criteria

Inclusion

  • Neuropathic bladder secondary to known neurological disorder
  • Elevated detrusor leak point pressures (LPP) ≥40 cm H2O confirmed by two measurements at baseline

Exclusion

  • Clinically significant abnormalities as determined by the investigator
  • A history of relevant orthostatic hypotension, fainting spells or blackouts

Key Trial Info

Start Date :

April 1 2006

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

June 1 2009

Estimated Enrollment :

143 Patients enrolled

Trial Details

Trial ID

NCT00340704

Start Date

April 1 2006

End Date

June 1 2009

Last Update

February 17 2016

Active Locations (72)

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Page 1 of 18 (72 locations)

1

Birmingham, Alabama, United States, 35233

2

Los Angeles, California, United States, 90027

3

Jacksonville, Florida, United States, 32207

4

Tampa, Florida, United States, 33614