Status:

COMPLETED

Scientific Protocol for the Study of Leukemia and Other Hematologic Diseases Among Clean-up Workers in Ukraine Following the Chernobyl Accident

Lead Sponsor:

National Cancer Institute (NCI)

Conditions:

Leukemia

Eligibility:

All Genders

18-70 years

Brief Summary

Leukemia holds a special place in the study of radiation-related cancer because bone marrow is one of the tissues most sensitive to the carcinogenic effect of ionizing radiation, radiogenic leukemia h...

Detailed Description

Leukemia holds a special place in the study of radiation-related cancer because bone marrow is one of the tissues most sensitive to the carcinogenic effect of ionizing radiation. Radiogenic leukemia h...

Eligibility Criteria

Inclusion

  • INCLUSION CRITERIA:
  • We intend to include in the proposed study all 350 clean-up workers with "historical" records and 150 proxies to be identified by the liquidators; however, we anticipate a considerable number of them will not be available for the study due to deaths, not being able to be traced, no response, refusals, etc. The study subjects will be interviewed in person. All study subjects are males, median age of early liquidators is 64 y while for clean-up workers sent to mission is about 61 years.
  • EXCLUSION CRITERIA:
  • Excluded from the study will be those who have been found to be deceased, cannot be located, refuse to participate in the study, or do not provide informed consent.

Exclusion

    Key Trial Info

    Start Date :

    August 26 1996

    Trial Type :

    OBSERVATIONAL

    Allocation :

    ACTUAL

    End Date :

    February 12 2020

    Estimated Enrollment :

    1779 Patients enrolled

    Trial Details

    Trial ID

    NCT00341016

    Start Date

    August 26 1996

    End Date

    February 12 2020

    Last Update

    February 21 2020

    Active Locations (1)

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    1

    Research Center for Radiation Medicine

    Kiev, Ukraine