Status:
COMPLETED
Maternal and Umbilical Cord Hormone Concentrations in Twin and Singleton Pregnancies
Lead Sponsor:
National Cancer Institute (NCI)
Conditions:
Normal Pregnancy
Eligibility:
FEMALE
18-60 years
Brief Summary
This study will examine levels of hormones, such as estrogen and testosterone, in maternal and umbilical cord blood to compare hormones between mothers who are having twins and mothers who are having ...
Detailed Description
Epidemiologic data are few but suggest that effects during the prenatal and early life periods may be important in influencing risk of breast, prostate and testicular cancers later in life. In particu...
Eligibility Criteria
Inclusion
- INCLUSION CRITERIA/EXCLUSION CRITERIA:
- Eligible for study are pregnant women 18 years of age and older.
- We will try to recruit women who do not have preeclampsia, chronic hypertension, pre-pregnancy or gestational diabetes, thyroid disease or other major pregnancy complications.
- CASES:
- Eligible women who are pregnant with twins.
- CONTROLS (Singletons):
- Three control groups will be recruited: two for the mother of twins (one at the third trimester, one at delivery), and one for the twins themselves at delivery.
- A singleton pregnancy that meets the eligibility criteria and can be matched to the case pregnancy on gestational age (within 1 week), parity (nulliparous vs. parous) and maternal age (+/- 5 years) will be recruited for study.
Exclusion
Key Trial Info
Start Date :
November 21 2003
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
February 19 2020
Estimated Enrollment :
111 Patients enrolled
Trial Details
Trial ID
NCT00341263
Start Date
November 21 2003
End Date
February 19 2020
Last Update
February 21 2020
Active Locations (1)
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1
Darmouth-Hitchcock Medical Center
Hanover, New Hampshire, United States, 03756