Status:
COMPLETED
Esophageal Cancer Genetics Studies
Lead Sponsor:
National Cancer Institute (NCI)
Conditions:
Esophageal Cancer
Gastric (Cardia, Body) Cancer
Eligibility:
All Genders
18+ years
Brief Summary
The overall goal of this project is to understand the role of genetics in the etiology and prevention of upper gastrointestinal cancer, primarily esophageal cancer, but also cancers of the gastric car...
Detailed Description
The overall goal of this project is to understand the role of genetics in the etiology and prevention of upper gastrointestinal cancer, primarily esophageal cancer, but also cancers of the gastric car...
Eligibility Criteria
Inclusion
- INCLUSION CRITERIA:
- All patients over the age of 18 presenting to the SCHI with upper GI signs or symptoms requiring upper GI endoscopy over a defined calendar period (depending on prevalence of premalignant lesions, but estimated to be approximately 3 years) will be potentially eligible for participation in this study.
- Patients are eligible only if they meet one of the following two conditions: (1) a visible lesion unlikely to be cancer or (2) no visible lesions on routine endoscopy (without mucosal iodine staining) but an unstained (abnormal) lesion following iodine spraying.
- Invitation for participation will be based solely on the visual appearance of an esophageal abnormality without or with mucosal iodine staining, but before histologic confirmation is obtained, and will occur during the same clinic visit as the qualifying endoscopic examination.
- EXCLUSION CRITERIA:
- Patients will not be invited to participate in this study until after they have undergone their routine endoscopic evaluation.
Exclusion
Key Trial Info
Start Date :
July 6 1995
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
March 18 2020
Estimated Enrollment :
7705 Patients enrolled
Trial Details
Trial ID
NCT00341276
Start Date
July 6 1995
End Date
March 18 2020
Last Update
October 30 2025
Active Locations (2)
Enter a location and click search to find clinical trials sorted by distance.
1
Shanxi Tumor Hospital and Institute
Taiyuan, China
2
Yangcheng County Cancer Hospital and Institute
Yangcheng, China