Status:

COMPLETED

A Nested Case-Control Study of Lung Cancer and Diesel Exhaust Among Non-Metal Miners

Lead Sponsor:

National Cancer Institute (NCI)

Conditions:

Lung Cancer

Eligibility:

All Genders

18+ years

Brief Summary

Diesel exhaust has been classified as a probable carcinogen by the International Agency for Research on Cancer and as a potential carcinogen by the National Institute for Occupational Safety and Healt...

Detailed Description

Diesel exhaust has been classified as a probable carcinogen by the International Agency for Research on Cancer and as a potential carcinogen by the National Institute for Occupational Safety and Healt...

Eligibility Criteria

Inclusion

  • INCLUSION AND EXCLUSION CRITERIA:
  • Subjects will be identified from all 10 mines participating in the cohort study.
  • Cases from each mine will be lung cancer deaths as specified on the death certificate occurring among members of the cohort working at the mine between the date the mine was dieselized and December 31, 1996.
  • Children will be excluded from participating.
  • We will exclude cases that are found either not likely to be carcinoma of the lung or metastatic to the lung by slide review or pathology report.
  • Four controls will be selected for each case by random sampling from among all members of the cohort who were alive prior to the day the case died.
  • Controls will be individually matched to the case on mine, gender, race/ethnicity, and year of birth (within 5 years).

Exclusion

    Key Trial Info

    Start Date :

    January 12 1999

    Trial Type :

    OBSERVATIONAL

    Allocation :

    ACTUAL

    End Date :

    April 16 2024

    Estimated Enrollment :

    1187 Patients enrolled

    Trial Details

    Trial ID

    NCT00342264

    Start Date

    January 12 1999

    End Date

    April 16 2024

    Last Update

    April 18 2024

    Active Locations (1)

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    Westat Inc

    Rockville, Maryland, United States, 20850