Status:
COMPLETED
Immunogenetics of Visceral Leishmaniasis
Lead Sponsor:
National Human Genome Research Institute (NHGRI)
Conditions:
Visceral Leishmaniasis
Eligibility:
All Genders
1+ years
Brief Summary
Visceral leishmaniasis is a potentially fatal disease caused in South America by the protozoan Leishmania chagasi. In neighborhoods with high exposure rates, the outcome of human infection with L. cha...
Detailed Description
Visceral leishmaniasis is a potentially fatal disease caused in South America by the protozoan Leishmania chagasi. In neighborhoods with high exposure rates, the outcome of human infection with L. cha...
Eligibility Criteria
Inclusion
- INCLUSION CRITERIA:
- We used three approaches to identify families in endemic neighborhoods, yielding three populations of families.
- Population I: A neighborhood to the northeast of the city was identified through a family with two cases of disease.
- Population 2: Individuals with suspected VL are admitted to one of three public hospitals in Natal. Families were interviewed and examined if they wished to participate.
- Population 3: The neighboring families living closest to population 2 families were identified.
- EXCLUSION CRITERIA
- Individuals with ongoing illnesses other than VL were excluded from analyses.
- Any medical conditions found or suspected based upon history, exam or blood tests were either treated by the investigators or referred to the appropriate medical facility in Natal.
- Pregnant women and children less than 1 year were not given any skin test.
- No exclusions based on ethnicity were done.
Exclusion
Key Trial Info
Start Date :
October 20 2003
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
June 30 2010
Estimated Enrollment :
7000 Patients enrolled
Trial Details
Trial ID
NCT00342823
Start Date
October 20 2003
End Date
June 30 2010
Last Update
July 2 2017
Active Locations (1)
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1
Universidade Federal do Rio Grande do Norte
Natal, Brazil