Status:
COMPLETED
Treatment of Lead-Exposed Children Trial
Lead Sponsor:
National Institute of Environmental Health Sciences (NIEHS)
Conditions:
Lead Exposure
Eligibility:
All Genders
12-33 years
Phase:
PHASE3
Brief Summary
The Treatment of Lead-Exposed Children (TLC) clinical trial compared the effect of lead chelation with succimer to placebo therapy. TLC was a randomized, double-blind, placebo-controlled clinical tria...
Detailed Description
At TLC enrollment, the children were between 12 and 33 months of age with baseline blood lead levels (PbB) between 20 and 44 microg/dl. Of 1,854 referred children who were screened for eligibility, 78...
Eligibility Criteria
Inclusion
- INCLUSION CRITERIA:
- The study population will reflect the population known to be at greatest risk to lead exposure, i.e., low income, urban, African-American children.
- EXCLUSION CRITERIA:
- Linguistic minorities will be excluded in all centers except Newark, where Hispanic children make up a sizable portion of the population and will be included.
Exclusion
Key Trial Info
Start Date :
July 15 1994
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
June 10 2015
Estimated Enrollment :
780 Patients enrolled
Trial Details
Trial ID
NCT00342849
Start Date
July 15 1994
End Date
June 10 2015
Last Update
April 5 2018
Active Locations (4)
Enter a location and click search to find clinical trials sorted by distance.
1
Kennedy Krieger Institute
Baltimore, Maryland, United States, 21205
2
University of Medicine and Dentistry of New Jersey
Newark, New Jersey, United States, 07103
3
Childrens Hospital, Columbus
Columbus, Ohio, United States, 43205-2696
4
Childrens Hospital, Philadelphia
Philadelphia, Pennsylvania, United States, 19104