Status:

COMPLETED

Intravenous Ancrod for the Treatment of Acute Ischemic Stroke Within 6 Hours After Onset of Symptoms

Lead Sponsor:

Heidelberg University

Conditions:

Brain Infarction

Cerebral Ischemia

Eligibility:

All Genders

18+ years

Phase:

PHASE3

Brief Summary

Treatment of acute stroke is still difficult and the only specific drug approved (rtPA) can only be administered if treatment starts within 3 hours after onset of symptoms. This results in a still too...

Eligibility Criteria

Inclusion

  • 18 years and above, both sexes
  • Acute ischemic stroke with first symptoms within 6 hours of beginning
  • Treatment after onset of symptoms
  • SSS \< 40 at baseline ( consciousness necessary )

Exclusion

  • Clinical or CT evidence of brain hemorrhage or hemorrhagic transformation
  • CT evidence of major signs of developing infarction
  • Coma
  • Prior strokes within 6 weeks
  • Severe hypertension (\> 220 systolic \> 120 mm Hg diastolic)
  • Baseline fibrinogen \< 100 mg/dL
  • Recent use of thrombolytic agents
  • Recent or anticipated surgery

Key Trial Info

Start Date :

Trial Type :

INTERVENTIONAL

End Date :

Estimated Enrollment :

Patients enrolled

Trial Details

Trial ID

NCT00343174

Last Update

June 22 2006

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Intravenous Ancrod for the Treatment of Acute Ischemic Stroke Within 6 Hours After Onset of Symptoms | DecenTrialz