Status:
COMPLETED
Novel Diagnostics With Optical Coherence Tomography: Imaging the Anterior Eye
Lead Sponsor:
NYU Langone Health
Collaborating Sponsors:
National Eye Institute (NEI)
Conditions:
Fuch's Dystrophy
Corneal Disorders
Eligibility:
All Genders
18-90 years
Brief Summary
The purpose of this research is to evaluate the optical coherence tomography (OCT), to image diseases of the eye. OCT may be useful for the early diagnosis and monitoring of a variety of diseases invo...
Detailed Description
The purpose of this research is to evaluate the optical coherence tomography (OCT), to image diseases of the eye. OCT may be useful for the early diagnosis and monitoring of a variety of diseases invo...
Eligibility Criteria
Inclusion
- Female Subjects who are pregnant or breastfeeding will be included (no risks to fetus).
- Normals: Normal appearing cornea, no history of corneal trauma, surgery or disease, no historical or current contact lens wear. Thirty subjects from 6 different age groups (\> 18 yrs; 20-30 yrs; 30-40 yrs; 40-50 yrs; 50-60 yrs; \> 60 yrs) will be recruited to determine the normal variations in anterior eye structure.
- LASIK patients: to participate as a LASIK patient, the subject is previously normal but may have worn contact lenses, and is scheduled to undergo LASIK.
- Contact lens wearers: to participate as a contact lens wearer the patient otherwise fulfills all criteria specified for normalcy, with the exception of contact lens wear.
- Fuchs' dystrophy patients: Fuchs' Dystrophy is characterized by guttata and clinically significant corneal edema, with a corneal thickness of \>700 microns, and/or reduced visual acuity in the morning which improves over the course of the day.
- Diabetic patients: for diabetic patients are specified in the posterior segment imaging section.
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Exclusion
- Subjects will be excluded from the study if their media are opaque, or if they are unwilling or unable to participate in the study.
- If participants choose they may also participate in other imaging research protocols. No risk is associated if entering multiple imaging protocols, while being a participant in this research study.
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Key Trial Info
Start Date :
October 1 2005
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
February 14 2024
Estimated Enrollment :
22 Patients enrolled
Trial Details
Trial ID
NCT00343473
Start Date
October 1 2005
End Date
February 14 2024
Last Update
July 1 2024
Active Locations (2)
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1
New York University School of Medicine
New York, New York, United States, 10016
2
University of Pittsburgh UPMC Eye Center
Pittsburgh, Pennsylvania, United States, 15213