Status:

COMPLETED

Opioid Maintenance Medications Comparison Study

Lead Sponsor:

Johns Hopkins University

Conditions:

Opioid Dependence

Eligibility:

All Genders

21-55 years

Phase:

PHASE2

Brief Summary

A 17 week, double-blind, randomized, parallel group, four arm design outpatient study comparing LAAM, buprenorphine and two dose levels of methadone for the treatment of opioid dependence.

Eligibility Criteria

Inclusion

  • Inclusion
  • age 21 to 55 years
  • diagnosis of opioid dependence by criteria of the Diagnostic and Statistical Manual of Mental Disorders, fourth edition (DSM-IV)
  • evidence of recent opioid use on toxicologic screening
  • Exclusion
  • serious medical or psychiatric illness requiring long-term medication
  • positive pregnancy test

Exclusion

    Key Trial Info

    Start Date :

    January 1 1996

    Trial Type :

    INTERVENTIONAL

    End Date :

    June 1 1998

    Estimated Enrollment :

    220 Patients enrolled

    Trial Details

    Trial ID

    NCT00344812

    Start Date

    January 1 1996

    End Date

    June 1 1998

    Last Update

    June 27 2006

    Active Locations (1)

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    1

    Behavioral Pharmacology Research Unit; Johns Hopkins Bayview Campus

    Baltimore, Maryland, United States, 21224