Status:
COMPLETED
The Effect of High and Low Sodium Intake on Urinary Aquaporin-2 in Healthy Humans.
Lead Sponsor:
Regional Hospital Holstebro
Conditions:
Healthy Humans
Eligibility:
All Genders
18-65 years
Phase:
NA
Brief Summary
The aim of the study is to test the hypothesis that the function and/or regulation of aquaporin 2 and/or endothelial sodium channels in the principal cells of healthy humans is abnormal at high and lo...
Eligibility Criteria
Inclusion
- Caucasic men and women
- Age 18-65 years
- Body mass index less or equal to 30 Kg/m2
Exclusion
- Arterial hypertension
- History or clinical signs of heart, brain, lung, kidney, malignant or endocrine organ disease.
- Abnormal biochemical screening of the blood regarding: red and white cell count, B-hemoglobin, P-sodium, P-potassium, P-creatinine, P-albumine, P- bilirubin, P-alanine aminotransferase, P- alkaline phosphatase, p-cholesterol and B-glucose.
- Abnormal screening of the urine regarding: blood, albumine and glucose.
- Alcohol or drug abuse
- Drug use except oral contraceptives
- Smoking
- Abnormal electrocardiogram
- Blood donation within one month of the first examination day
- Pregnancy
- Unwillingness to participate
Key Trial Info
Start Date :
May 1 2006
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
May 1 2007
Estimated Enrollment :
26 Patients enrolled
Trial Details
Trial ID
NCT00345215
Start Date
May 1 2006
End Date
May 1 2007
Last Update
June 28 2011
Active Locations (1)
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1
Department of Medical Research, Holstebro Hospital
Holstebro, Holstebro, Denmark, 7500