Status:
COMPLETED
Effects of Systane Versus Saline in Maintaining Tear Film Stability at Determined Time Points
Lead Sponsor:
University of Texas Southwestern Medical Center
Conditions:
Keratoconjunctivitis Sicca
Eligibility:
All Genders
18-88 years
Phase:
NA
Brief Summary
To evaluate tear film stability of a market lubricant therapeutic eye drop versus saline when using Evaporometry and Interferometry in patients with a diagnosis of Keratoconjunctivitis Sicca (KCS). Th...
Detailed Description
The goal of this research is to evaluate and compare the effectiveness of Systane® versus saline on aqueous tear film stability in patients with a diagnosis of Dry Eye Syndrome and to determine the po...
Eligibility Criteria
Inclusion
- Individuals in good health with signs of Keratoconjunctivitis Sicca are the primary subject population. An ophthalmologist will perform a thorough ocular exam in order to assess entrance qualification into the clinical trial. Patients with apparent Aqueous Tear Deficiency (ATD) with or without slit lamp findings of Meibomian lipid turbidity or difficulty in expression of Meibomian Gland Secretion (MGD) with ocular surface vital staining consistent with ATD in the absence of concurrent disease including lid or ocular surface inflammation beyond 1+ bulbar conjunctival injection will be enrolled.
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Exclusion
- Patients with active systemic disease or those taking systemic medication that are known to influence AT production will not be considered for this trial. In addition, patients using topical medication who are unable to discontinue them for at least 24 hours prior to baseline evaluation will be excluded as well.
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Key Trial Info
Start Date :
January 1 2006
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
December 1 2006
Estimated Enrollment :
12 Patients enrolled
Trial Details
Trial ID
NCT00345241
Start Date
January 1 2006
End Date
December 1 2006
Last Update
June 23 2008
Active Locations (1)
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1
University of Texas Southwestern Medical Center at Dallas
Dallas, Texas, United States, 75390-8866