Status:

COMPLETED

Clinical Study Assessing Idrabiotaparinux Sodium Injections Once-weekly in Pulmonary Embolism Therapeutic Approach

Lead Sponsor:

Sanofi

Conditions:

Embolism

Thrombosis

Eligibility:

All Genders

18+ years

Phase:

PHASE3

Brief Summary

Objectives are to evaluate whether idrabiotaparinux sodium (SSR126517E) is as least as effective as a standard warfarin treatment to prevent recurrence of venous thromboembolic events (VTE) in patient...

Detailed Description

Treatment with a therapeutic dose of any low molecular weight heparin (LMWH) or unfractioned heparin (UFH) or fondaparinux is allowed only within the 36 hours immediately preceding randomization. Rand...

Eligibility Criteria

Inclusion

  • Symptomatic pulmonary embolism with or without symptomatic deep vein thrombosis

Exclusion

  • End stage renal failure, hepatic failure, uncontrolled hypertension;
  • Active bleeding or high risk for bleeding;
  • Pregnancy or childbearing potential without proper contraceptive measures, threatened abortion.
  • Breastfeeding.
  • Known allergy to idraparinux or idrabiotaparinux, avidin or egg proteins;
  • hypersensitivity to warfarin, enoxaparin, heparin or pork product; or any other contraindication listed in the labelling of warfarin or enoxaparin;
  • Indication of prolonged anticoagulation therapy for other reason than PE;
  • Life expectancy \< 6 months;

Key Trial Info

Start Date :

June 1 2006

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

October 1 2010

Estimated Enrollment :

3202 Patients enrolled

Trial Details

Trial ID

NCT00345618

Start Date

June 1 2006

End Date

October 1 2010

Last Update

March 21 2016

Active Locations (38)

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Page 1 of 10 (38 locations)

1

Sanofi-Aventis Administrative Office

Bridgewater, New Jersey, United States, 08807

2

Sanofi-Aventis Administrative Office

Buenos Aires, Argentina

3

sanofi-aventis Australia & New Zealand administrative office

Macquarie Park, New South Wales, Australia

4

Sanofi-Aventis Administrative Office

Vienna, Austria