Status:

COMPLETED

Rituximab in Primary Lymphocyte Predominant Hodgkin´s Disease(RIPL)

Lead Sponsor:

University of Cologne

Conditions:

Lymphocyte Predominant Hodgkin´s Lymphoma (LPHD)

Eligibility:

All Genders

18-75 years

Phase:

PHASE2

Brief Summary

First line therapy for patients with Lymphocyte predominant Hodgkin´s Disease (LPHD) in clinical stage IA using the monoclonal anti-CD20 antibody rituximab

Eligibility Criteria

Inclusion

  • lymphocyte predominant Hodgkin´s lymphoma (histologically proven)
  • clinical stage IA (without risk factors: large mediastinal mass, extranodal involvement, ESR \> 50mm/h)
  • age 18 - 75
  • WHO performance status 0-3
  • normal organ function
  • written informed consent

Exclusion

  • classical Hodgkin´s lymphoma
  • composite lymphoma
  • leucocytes \< 3000/µl
  • thrombocytes \< 100.000/µl

Key Trial Info

Start Date :

July 1 2006

Trial Type :

INTERVENTIONAL

End Date :

Estimated Enrollment :

Patients enrolled

Trial Details

Trial ID

NCT00346684

Start Date

July 1 2006

Last Update

August 12 2008

Active Locations (1)

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Page 1 of 1 (1 locations)

1

University of Cologne

Cologne, Germany, 50931