Status:

TERMINATED

Mitral Valve Reconstruction in Chronic Heart Failure (CHF): Identification of Predictors for a Successful Therapy

Lead Sponsor:

University of Leipzig

Conditions:

Chronic Heart Failure

Mitral Insufficiency

Eligibility:

All Genders

18-70 years

Phase:

PHASE2

Brief Summary

The aim of the study is to evaluate hemodynamic and echocardiographic parameters in patients with secondary mitral insufficiency and CHF. 1. Identification of hemodynamic parameters as predictor for ...

Eligibility Criteria

Inclusion

  • Age \> 18 years old
  • Dilatative Cardiomyopathy with LVEF \< 35%
  • NYHA III oder IV under maximal medical treatment
  • Angiographic and hemodynamic MI \> II° (LAP- mean pressure \> 15-20 mmHg; LA v-wave-oder PCWP v-wave \> 35 mmHg under exercise)
  • Echocardiographic MI \> II°
  • At least 1 hospitalization for heart failure before OP

Exclusion

  • Secondary Cardiomyopathy by vitium cordis
  • Planned secondary procedure like CABG, aortic valve surgery, surgery of the tricuspid valve etc
  • Inclusion in another trial
  • Euro-Score \> 30%
  • Former valve operation or CABG

Key Trial Info

Start Date :

June 1 2006

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

September 1 2012

Estimated Enrollment :

5 Patients enrolled

Trial Details

Trial ID

NCT00348829

Start Date

June 1 2006

End Date

September 1 2012

Last Update

October 27 2016

Active Locations (1)

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1

Heart Center Leipzig GmbH, University Leipzig

Leipzig, Germany, 04289